Toxoplasma gondii antibody
Release time : 12/13/2024 08:47:49
The risk of toxoplasmosis is high and mostly asymptomatic.
Through detecting Toxoplasma antibody, we can better understand the infection.
The antibodies against Toxoplasma gondii are of two types, IgM and IgG.
Its nucleic acid is DNA.
Toxoplasma antibody, Toxoplasmosis is a zoonotic disease that can cause central nervous system and ocular lesions. Infected pregnant women can transmit the infection to fetuses through the placenta, leading to spontaneous abortions and congenital deformities.
Moreover, most people with infection are asymptomatic, and we can only detect the antibodies to understand the situation. Then what is Toxoplasma antibody? There are two types of Toxoplasma antibody, IgM and IgG.
Its nucleic acid is DNA.
The reference values for IgG and IgM in the laboratory were all negative by indirect hemagglutination test, IFA and ELISA.
An increase in IgM is a marker of recent infection, while an increase in IgG indicates prior infection.
Double serum IgG antibody titers more than four times increased, or single serum IgG antibody titer ≥1:512, suggest the possibility of recent infection is high.
The IgG antibody to Toxoplasma gondii is positive. Its final hosts are cats and feline animals, and the main source of infection is cysts and oocysts which are present in the feces of feline animals.
Through various means of contamination, any animal that ingests food containing cysticercosis cysts, eggs or live parasites will be infected.
At present, it is known that 140 different animals have been infected by the virus.
Due to the fact that infections often present as asymptomatic, only testing antibodies can provide evidence. When an IgG antibody to Toxoplasma is detected, it means the following: 1) The individual has been previously infected; Toxoplasma infection in most cases does not manifest symptoms. Generally speaking, people who are infected will recover within a few days or weeks as their own antibodies strengthen, but this virus cannot be completely eliminated from the body. It remains dormant and hidden in the host, and IgG will always show a positive reaction, indicating a previous infection.
Currently, it is essential to ascertain whether one is in the infectious period. Only through laboratory data can we determine this. A two-fold serum IgG antibody titer increase by more than four times or a single serum IgG antibody titer of ≥1:512 indicates a high likelihood of recent infection.
The presence of positive IgM antibodies to Toxoplasma indicates that you are currently infected with Toxoplasma and are in the early stages of infection.
Toxoplasma gondii is typically asymptomatic in the human host, and only a minority of individuals are infected with the parasite without exhibiting any symptoms. Confirmation of Toxoplasma infection can only be achieved through laboratory testing.
The presence of an IgM antibody in a sample is considered definitive evidence of current infection.
Although a considerable number of people can recover without treatment as their immunity increases.
But when you detect a positive result, it's best to consult a doctor for their opinion and decide accordingly.
However, if a pregnant woman contracts it, she must seek medical advice and treat the condition because Toxoplasma gondii can be transmitted to the fetus through the placenta, potentially leading to congenital abnormalities or even death in severe cases.
Toxoplasma antibody test is a zoonotic disease, the sources of which are mainly cats and their felids. It can infect more than 140 kinds of animals including human beings.
If an immunocompromised patient or pregnant woman is infected, it will cause greater harm.
However, most people infected with Toxoplasma gondii do not exhibit any symptoms, so we need to draw blood serum for Toxoplasma antibody testing to understand our infection status.
Under normal circumstances, when we visit a hospital for examination, we generally only undergo testing for antibodies IgM unless there is an explicit request. This is because antibody IgM reflects the current infection status.
A negative result indicates that there is no infection at the current time; a positive result signifies that there was an infection at the time of testing.
In fact, after being infected with Toxoplasma gondii, it can usually heal spontaneously in a few days or weeks as the body's immune system develops.
After recovery, IGM will automatically turn negative.
In order to determine whether we have been infected previously, we must check for antibodies IgG. A positive result indicates that we have been infected in the past, while a negative result means we have never been infected.
Individuals in need of this kind of information may consult a doctor.
The medical information provided in this text is for reference only.
If discomfort arises, it is recommended to seek medical attention immediately. The diagnosis and treatment should be based on a consultation in person.