Herpes simplex virus type 2
Release time : 12/13/2024 10:47:36
Herpes Simplex Virus is globally widespread and highly prevalent among the population, with numerous individuals experiencing latent or recurrent infections.
Patients and carriers are the source of infection with herpes simplex virus.
Viruses can enter the body through direct contact with the skin or mucous membranes, or sexual contact.
Herpes Simplex Virus Type 2, mainly transmitted through sexual contact, poses significant threats to both the individual and their offspring.
Herpes Simplex Virus 2 (HSV-2) is what? Herpes simplex virus belongs to the Herpesviridae family and the Aphthovirus genus. The virus particle size is approximately 180 nanometers. Herpes Simplex Virus (HSV) is a DNA virus, appearing as a spherical structure, consisting of a nucleocapsid and an enveloped viral capsid.
Based on antigenic differences, they are divided into Type 1 and Type 2.
Type 1 is primarily acquired from oral and labial lesions, while type 2 can be isolated from genital lesions. Type 2 is generally harder to cure.
HSV has a weak resistance to external factors. It can be inactivated by heating at 56°C for 30 minutes, ultraviolet radiation for 5 minutes, or by ether and other lipid solvents.
2-Type mainly spread through sexual contact, genital herpes is one of the recurring and difficult to cure sexually transmitted diseases. It is caused by simplex type II herpes virus, which is quite tenacious. To cure it, it must be completely killed all the toxins within.
HSV-2 primarily causes infections in the genital area or newborns, but there is no strict boundary between the two types of virus infection.
Neonates may acquire the HSV-1 infection through the birth canal from a mother with vaginal condyloma acuminata, or by ascending from the cervix.
Furthermore, research has demonstrated that patients with recurrent herpes simplex virus can have a defect in cellular immunity. It is generally considered that Herpes Simplex Virus Type 2 is associated with the occurrence of cervical cancer.
Herpes simplex virus type 2 mainly exists in the skin of the cervix, vagina, and external genitalia of females, as well as in the penis and urethra of males. It is the main cause of genital inflammation and herpes, and both men and women can be infected, making it the main culprit of genital inflammation and herpes.
Following an HSV infection of the genital area, a burning sensation is initially experienced in the vulvar lesion, which subsequently develops into clusters of papules or more than one cluster. Subsequently, these papules evolve into vesicles.
Several days later, it evolved into pustules, which ruptured to form erosions or superficial ulcers, causing pain and eventually healed by scab formation.
According to statistics, 90% of the causative agent of genital herpes is type II herpesvirus, and only 10% is type I.
Following sexual contact, the incubation period is approximately 2-20 days. In individuals with immunodeficiencies or compromised immune function, such as those on immunosuppressive agents, renal transplant recipients, severe burns, malnutrition, and those with malignant lymphoproliferative diseases, symptoms may worsen following infection, potentially leading to herpes zoster eruptions, recurrent corneal ulcers, and even systemic disseminated herpes fatalities.
1-3 weeks after infection, the body produces neutralizing antibodies and complement binding antibodies, the residual virus may enter the trigeminal ganglion or sacral nerve ganglion along the nerve axis, and remain in a dormant state.
When certain inducers, such as anxiety, trauma, exposure to cold or sunlight, wind blowing, trauma, infection, drug allergy, high fever, menstruation, pregnancy, etc., destroy the physiological balance of the body, specific transcription enzyme needed for virus proliferation appears in nerve cells, activates the virus and leads to recurrence. Body fluid antibodies cannot stop the recurrence of herpesvirus, and weakened cell immunity has a significant impact on recurrence.
The IgG of Herpes Simplex Virus Type 2 has a self-limiting course, and recovery occurs within 1-2 weeks.
The purpose of treatment is to prevent future recurrence.
Currently, there are no specific drugs available for this disease. The treatment principle is to shorten the course of the disease, prevent secondary infections, and reduce relapses.
How to treat the IgG antibody of herpes simplex virus 2? 1. Local therapy: The principle is dryness, closure, protection of the affected area and prevention of secondary infection.
External application of 2% Gentian Violet solution, or 10% St. John's Bitter Orange Pill (Dermatol), Ointment or Ointment containing Zinc Oxide, Lilac and Licorice Ointment, or 0.5% Neomycin Ointment, or 0.25% - 0.1% Herpes Zoster (IDU) ointment, 5% Herpes Zoster Dimethyl Sulfoxide solution may be used.
For the face, 10% aluminium chloride or zinc and copper compound may be used.
2. Systemic Treatment: The principle of systemic treatment is to inactivate or even eliminate the HSV, preventing its activation.
Second, immune regulation and the prevention of recurrence can be achieved with acyclovir intravenous drip or oral administration, ribavirin oral intake, interferon injection, and interleukin-2 injection.
Traditional Chinese medicine has accumulated many very effective treatment methods through long-term clinical practice. It is recommended to use traditional Chinese herbal remedies such as Pangolin, Rhizoma Coptidis, Herba Heterophyllae, Radix Paeoniae Rubra, Ferrous Arginate, Hainan Feng, Isatis Indigotica, Herba Chrysanthemum, Radix Rehmanniae, and Herba Artemisiae Scopariae for treatment. The efficacy is definite, and many patients are cured without recurrence. This can produce an endogenous interferon in the body, which blocks the replication of the herpes simplex virus DNA, just like being tied up, preventing the production of new viruses, thus thoroughly eliminating the herpes simplex virus and achieving a cure.
What should be done if a pregnant woman has only IgG antibody to herpes simplex virus type 2 and is positive for the infection? Pregnant women with genital herpes generally face serious adverse effects on the fetus. However, what does it mean when a pregnant woman has only IgG antibody to herpes simplex virus type 2? Let's take a look at a case: Patient: She is one month pregnant and underwent a comprehensive prenatal screening, which revealed that one of the IgG levels was positive, while the other two were negative.
Does this result have any impact on the fetus? The doctors at the hospital where I underwent the examination advised against having the child.
However, upon researching extensively online, I found that IgG positivity does not affect the fetus.
Answer: Cytomegalovirus infection during pregnancy can lead to fetal malformation. Therefore, prenatal examinations should be conducted. Your IgG antibody test is positive, not IgM. This indicates that you were not infected recently; it means you have been exposed to cytomegalovirus and have developed antibodies, which means you possess some immunity. Currently, there is no need for special treatment.
Generally, IGG reflects a potential infection in the distant future. However, since you have not undergone any examination before becoming pregnant, it is currently only necessary to closely monitor the fetus's condition and conduct regular prenatal check-ups.
After a pregnant woman is diagnosed with herpes simplex virus infection, it is not certain that the virus will transmit to the fetus. Therefore, an amniocentesis should be performed promptly. If the results of the amniocentesis show positive for the virus, termination of pregnancy should be considered.
For primigravida with placental infection, cesarean section should be performed before membrane rupture or within 3 hours after membrane rupture to protect the newborn from infection.
To have a healthy baby, it is advisable to seek treatment at a reputable and specialized maternity hospital.
The medical information provided in this text is for reference only.
In case of discomfort, it is recommended to seek immediate medical attention for an accurate diagnosis and treatment.